Reducing Pulsation in Bioprocessing
In bioprocessing, achieving the best results requires optimizing every detail. Reducing pulsation is often a necessary factor to enhance process control, improve product quality, and save costs. Pulsation causes fluctuations in flow rates, leading to inconsistent fluid delivery - when pulsation is minimized, flow becomes smooth and steady.
It's a small adjustment with big benefits for your operations. Here's how a simple change can make a big difference:
Better Process Control and Stability
Reducing pulsation helps maintain steady flow rates and stable pressure, ensuring consistent conditions throughout the process. Stable conditions result in more accurate sensor readings and process monitoring. This precision helps to better control parameters like pH, conductivity, and temperature, for more consistent results.
Enhanced Product Quality
The controlled and reproducible conditions help ensure that what works on a small scale will also work on a larger scale. With less pulsation, you minimize shear stress on sensitive cells and proteins. This leads to higher quality products, as cells and proteins maintain their integrity and activity. Processes with less pulsation are easier to scale up from lab to industrial scale.
Five Is Smoother Than Four
AlphaBio Systems bring innovation to process design. Using Alphinity’s 5-diaphragm PIXER®, we achieve 77% less pulsation than a 4-diaphragm pump, for unmatched liquid pressurization in downstream operations.
